DataVXSmallPaper
journal article·2022-07

Biocoating—A Critical Step Governing the Oral Delivery of Polymeric Nanoparticles (Small 26/2022)

Aharon Azagury, Cameron Baptista, Kosta Milovanovic, Hyeseon Shin, Peter Morello, James Perez‐Rogers, Victoria Goldenshtein, Travis Nguyen, Arianna Markel, Soham Rege, Stephanie Hojsak, Alexander Perl, Carder Jones, Megan Fife, Stacia Furtado, Edith Mathiowitz

Small· Volume 18· Issue 26
Publisher page
Source abstract

Abstract

Biocoating In article number 2107559, Edith Mathiowitz and co-workers characterize the effects of nanoparticles (NPs) interaction with gut mucins. Mucins biocoating alters the surface charge, effective size, mucosal diffusion coefficient, and the extent of NPs aggregation. The implementation of this natural phenomenon may improve in vitro to in vivo correlation and alleviate long-lasting controversies regarding bioadhesive NPs and the appropriate surface charge for oral drug delivery.
Source: openalex_inverted_index · Quality: baseline

Research context

PolymersNanomaterials

OpenAlex topics: Advanced Drug Delivery Systems

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Noninvasive Biomimetic Drug Delivery Systems Lab The Department of Chemical Engineering Ariel Center for Applied Cancer Research (ACACR) Ariel University Ramat HaGolan St 65 Ari'el 40700000 Israel

Department of Pathology and Laboratory Medicine Center of Biomedical Engineering Brown University 171 Meeting Street, Box G‐B3 Providence RI 02912 USA

References

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