journal article·2022-06

Precisely Localized Bone Regeneration Mediated by Marine‐Derived Microdroplets with Superior BMP‐2 Binding Affinity (Small 24/2022)

Eun Young Jeon, Seung‐Hoon Um, Jaeho Park, Youngmee Jung, Cheol‐Hong Cheon, Hojeong Jeon, Justin J. Chung

Small· Volume 18· Issue 24
Publisher page

Abstract

Bone Regeneration In article number 2200416, Hojeong Jeon, Justin J. Chung, and co-workers fabricate complex coacervate of fucoidan and poly-l-lysine to prevent bone morphogenetic protein-2 (BMP-2) leakage from collagen sponges. The microencapsulation ability of the coacervate significantly enhances BMP-2 bioactivity and provides protection against antagonist and proteolysis. Moreover, the BMP-2 containing coacervate allows bone regeneration precisely within the defect site.
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Research context

OpenAlex topics: Periodontal Regeneration and Treatments · Bone Tissue Engineering Materials

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Affiliations

Biomaterials Research Center Biomedical Research Division Korea Institute of Science and Technology Seoul 02792 Republic of Korea

Department of Materials Science and Engineering Seoul National University Seoul 08826 Republic of Korea

School of Electrical and Electronic Engineering Yonsei University Seoul 03722 Republic of Korea

Yonsei‐KIST Convergence Research Institute Seoul 03722 Republic of Korea

Department of Chemistry Korea University Seoul 02841 Republic of Korea

KU‐KIST Graduate School of Converging Science and Technology Korea University Seoul 02841 Republic of Korea

Transdisciplinary Department of Medicine and Advanced Technology Seoul National University Hospital Seoul 03080 Republic of Korea

Department of Medicine Seoul National University College of Medicine Seoul 03080 Republic of Korea

References

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