DataVXSmallPaper
journal article·2022-05Open access

Tumor Customized 2D Supramolecular Nanodiscs for Ultralong Tumor Retention and Precise Photothermal Therapy of Highly Heterogeneous Cancers (Small 21/2022)

Peng Lin, Yucheng Xue, Xueluer Mu, Youyou Shao, Qian Lu, Xiangang Jin, Eloy Yinwang, Zengjie Zhang, Hao Zhou, Wangsiyuan Teng, Hangxiang Sun, Weida Chen, Wei Shi, Cangyi Shi, Xianfeng Zhou, Xuesheng Jiang, Xiaohua Yu, Zhaoming Ye

Small· Volume 18· Issue 21
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Source abstract

Abstract

Photothermal Therapy In article number 2200179, Xuesheng Jiang, Xiaohua Yu, Zhaoming Ye, and co-workers introduce a strategy of precise photothermal therapy for highly heterogenous cancers by a tumor-customized 2D supramolecular nanodisc (T-ND). By modifying Cy7-TCF crystal with phage display derived tumor-customized binding peptides, T-ND shows excellent photothermal efficacy to ablate the tumor and achieves ultralong retention time of more than 24 days in the “off-target” tumor site.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Supramolecular Self-Assembly in Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Orthopedics Research Institute of Zhejiang University Department of Orthopedic Surgery The Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou 310000 P. R. China

Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province Hangzhou Zhejiang 310000 P. R. China

Key Lab of Biobased Polymer Materials of Shandong Provincial Education Department College of Polymer Science and Engineering Qingdao University of Science and Technology Qingdao Shandong 266042 P. R. China

Department of Nephrology Children's Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310000 P. R. China

Department of Orthopedics Huzhou Hospital Zhejiang University Huzhou Central Hospital Huzhou Zhejiang 313000 China

References

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