Contents: (Small 23/2014)

NanoprobesHydrogen sulfi de (H2S) is an important gaseous signaling agent mediated by many physiological processes.However, current downconversion H2S probes are impractical for bioimaging due to the short tissue penetration of UV/visible light.As reported by J. S. C. Loo, Q. Zhang, and co-workers on page 4874, a new design for the NIRexcited imaging of H2S is developed by using coumarin-hemicyanine (CHC1)-modifi ed upconversion nanophosphors.This work can be further developed as a diagnostic tool for the detection of H2S-induced infl ammatory diseases.