Contents: (Small 29/2016)

GrapheneOn page 3956, A. Yurtsever and co-workers demonstrate a novel method to obtain a p-doped graphene layer on SiC (0001) substrate by Pb atom intercalation.The Pb intercalated structure is found to be stable in ambient conditions and at high temperatures up to 1250 °C.It is shown that electronic properties of graphene can be greatly tuned by Pb intercalation on SiC, which can facilitate the use of graphene in the various fi elds such as superconductivity and spintronics. NanocompositesThe encapsulation of single plasmonic nanoparticles within ZIF-8 is presented by I. Pastoriza-Santos, J. Pérez-Juste, and co-workers on page 3935.Different surfactantstabilised plasmonic nanoparticles were encapsulated within ZIF-8 nanocrystals.The plasmonic core allowed the study of the transport of different guests inside the ZIF-8 shell by means of surface-enhanced Raman scattering (SERS).The fl exibility of the ZIF-8 shell is demonstrated through the diffusion of molecules larger than the nominal aperture size. Cancer TreatmentOn page 3985, F. J. Gruhl, A. C. B. Cato engineer superporous poly(ethylene glycol) diacrylate cryogels that mimic the stiffness of malignant prostate tissues for studies of prostate cancer cell growth and function.Cells grow in an anchorage-dependent manner in this scaffold for three weeks and respond to androgen and antiandrogen treatment.Compared to 2D cell culture system, androgen-dependent prostate target gene expression is highly regulated in this system.