Contents: (Small 6/2017)

cover pictures Virus CaptureIn article number 1603135, S.-Y.Zheng and co-workers develop a point of care device integrated with porous silicon nanowire forests for influenza virus capturing based on their sizes only.By dissolving nanowire forests in physiological aqueous environments, subsequently captured viruses could be released without damage for culturing, characterization, and other analysis.The device shows potential for virus discovery, isolation, and functional studies NanotheranosticsIn article number 1602580, J. Lin, P. Huang, Y. Xu, Z. Li, and co-workers present a light/pH dual-stimuli responsive nanotheranostic for multimodal imaging such as two-photon luminescence, fluorescence, photoacoustic, photothermal imaging, as well as trimodal synergistic therapy such as photothermal therapy, photodynamic therapy, and chemotherapy.The cover image depicts how this activatable theranostic nanoplatform fights against cancer like "ten thousand arrows shot at once". Upconversion NanoparticlesInnovative strategies to unleash the freedom of the excitation wavelengths of upconversion nanoparticles have recently been developed.In article number 1602843, W. Huang, G. Han, and co-workers comprehensively review recent advances in the design, property tuning, and applications of ≈800 nm excited upconversion nanoparticles.These nanoparticles show superior potential for biosensing, bioimaging, drug delivery, and therapy.