journal article·2021-08Open access

Continuous Monitoring Reveals Protective Effects of N‐Acetylcysteine Amide on an Isogenic Microphysiological Model of the Neurovascular Unit (Small 32/2021)

Isabelle Matthiesen, Dimitrios Voulgaris, Polyxeni Nikolakopoulou, Thomas E. Winkler, Anna Herland

Small· Volume 17· Issue 32

Abstract

Microphysiological Systems In article number 2101785, Thomas E. Winkler, Anna Herland, and co-authors describe a microphysiological blood-brain barrier model that captures the multicellular interactions of iPS-derived cells. The integrated electrical sensors, facilitated by PDMS-free fabrication, allow for real-time monitoring of how the barrier responds to oxidative stress and antioxidant prophylaxis.
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Research context

OpenAlex topics: Neurological Disorders and Treatments

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Affiliations

Division of Micro‐ and Nanosystems KTH Royal Institute of Technology Malvinas Väg 10 pl 5 Stockholm 100 44 Sweden

AIMES, Center for Integrated Medical and Engineering Sciences Department of Neuroscience Karolinska Institute Solnavägen 9/B8 Solna 171 65 Sweden

References

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