DataVXSmallPaper
journal article·2022-02

Microfluidic Size Exclusion Chromatography (μSEC) for Extracellular Vesicles and Plasma Protein Separation (Small 6/2022)

Sheng Yuan Leong, Hong Boon Ong, Hui Min Tay, Fang Kong, Megha Upadya, Lingyan Gong, Ming Dao, Rinkoo Dalan, Han Wei Hou

Small· Volume 18· Issue 6
Publisher page
Source abstract

Abstract

Extracellular Vesicle Isolation Extracellular vesicles (EVs) are cell-derived nanovesicles (≈5–200 nm) which play important roles in intercellular communication. In article number 2104470, Han Wei Hou and co-workers report a low-cost microfluidic size exclusion chromatography (μSEC) platform integrated with an on-chip nanoliter sample plug injector for direct EV isolation from human plasma. Its portable and modular design allows flexible coupling with downstream detection modules for clinical diagnostics and real-time EV process monitoring.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Extracellular vesicles in disease

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Mechanical and Aerospace Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore

School of Biological Sciences Nanyang Technological University 60 Nanyang Drive Singapore 637551 Singapore

Department of Material Science and Engineering Massachusetts Institute of Technology 77 Massachusetts Avenue Cambridge MA 02139 USA

Endocrine and Diabetes Tan Tock Seng Hospital 11 Jalan Tan Tock Seng Singapore 308433 Singapore

Lee Kong Chian School of Medicine Nanyang Technological University 11 Mandalay Road, Clinical Sciences Building Singapore 308232 Singapore

References

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