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journal article·2022-02Open access

Diffusion Behaviors of Integrins in Single Cells Altered by Epithelial to Mesenchymal Transition (Small 5/2022)

Jing‐Wen Yuan, Yu‐Ning Zhang, Yu‐Ru Liu, Wei Li, Shuo‐Xing Dou, Yan Wei, Peng‐Ye Wang, Hui Li

Small· Volume 18· Issue 5
Publisher pageOpen full text
Source abstract

Abstract

Epithelial to Mesenchymal Transition The cover image shows that the malignant cells generated by the epithelial-mesenchymal transition (EMT) are breaking away from the benign ones and spreading elsewhere. In article number 2106498, using single-particle tracking of β1-integrins labelled with fluorescent quantum dots, Yan Wei, Peng-Ye Wang, Hui Li, and co-workers discover a significantly enhanced diffusion of integrins on cell membranes after EMT, which may represent a new hallmark of EMT and offer a novel method for cancer diagnosis.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Cancer-related molecular mechanisms research · Cancer Cells and Metastasis · Ferroptosis and cancer prognosis

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Affiliations

Beijing National Laboratory for Condensed Matter Physics and Laboratory of Soft Matter Physics Institute of Physics Chinese Academy of Sciences Beijing 100190 China

School of Physical Sciences University of Chinese Academy of Sciences Beijing 100049 China

Department of Orthodontics Peking University School and Hospital of Stomatology Beijing 100081 China

Songshan Lake Materials Laboratory Dongguan Guangdong 523808 China

Beijing Laboratory of Biomedical Materials Department of Geriatric Dentistry Peking University School and Hospital of Stomatology Beijing 100081 China

School of Systems Science and Institute of Nonequilibrium Systems Beijing Normal University Beijing 100875 China

References

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