Integrated Addressable Dynamic Droplet Array (aDDA) as Sub‐Nanoliter Reactors for High‐Coverage Genome Sequencing of Single Yeast Cells (Small 37/2021)
Source abstract
Abstract
Single-Cell Genome Sequencing In article number 2100325, Chunyu Li, Bo Ma, and co-workers present an addressable dynamic droplet array (aDDA) that combines the advantages of static droplet arrays and continuous-flow droplet platforms. All the sample preparation steps including single-cell isolation, cell lysis, and amplification are performed in sequence within a sub-nanoliter (≈300 pL) droplet, resulting in highly uniform whole genome amplification.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Single-cell and spatial transcriptomics
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Affiliations
Single‐Cell Center CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of Sciences Qingdao Shandong 266071 China
References
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