DataVXSmallPaper
journal article·2021-05

Microfluidics: Direct and Label‐Free Cell Status Monitoring of Spheroids and Microcarriers Using Microfluidic Impedance Cytometry (Small 21/2021)

Lingyan Gong, Chayakorn Petchakup, Pujiang Shi, Pei Leng Tan, Lay Poh Tan, Chor Yong Tay, Han Wei Hou

Small· Volume 17· Issue 21
Publisher page
Source abstract

Abstract

Non-invasive and real-time monitoring of microcarriers and three-dimensional cell cultures are important in biomanufacturing and bioprocesses. In article number 2007500, Han Wei Hou and co-workers introduce a low-cost microfluidic impedance cytometer with Field's metal electrodes for label-free and continuous-flow monitoring of spheroids/microcarriers based on changes in impedance signatures. Potential applications include tracking of cell proliferation (biomass), cell viability and stem cell differentiation on hydrogel and commercial microcarriers.
Source: openalex_inverted_index · Quality: baseline

Research context

Polymers

OpenAlex topics: Microfluidic and Bio-sensing Technologies

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Affiliations

School of Mechanical and Aerospace Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798

School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798

School of Biological Sciences Nanyang Technological University 60 Nanyang Drive Singapore 637551

Environmental Chemistry and Materials Centre Nanyang Environment and Water Research Institute 1 CleanTech Loop, CleanTech One Singapore 637141

Energy Research Institute Nanyang Technological University Singapore 50 Nanyang Drive Singapore 637553

Lee Kong Chian School of Medicine Nanyang Technological University 11 Mandalay Road Singapore 308232

Critical Analytics for Manufacturing of Personalized Medicine Singapore‐Massachusetts Institute of Technology Alliance for Research and Technology 1 CREATE Way, #10‐01, CREATE Tower Singapore 138602

References

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