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journal article·2021-04Open access

Drug Screening Tools: A Spheroid‐Forming Hybrid Gold Nanostructure Platform That Electrochemically Detects Anticancer Effects of Curcumin in a Multicellular Brain Cancer Model (Small 15/2021)

Intan Rosalina Suhito, Novi Angeline, Kwang‐Ho Lee, Huijung Kim, Chun Gwon Park, Zhengtang Luo, Tae‐Hyung Kim

Small· Volume 17· Issue 15
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Source abstract

Abstract

In article number 2002436, Tae-Hyung Kim and co-workers demonstrate a novel multifunctional hybrid platform that enables spontaneous cancer spheroids formation on the surface and real-time non-destructive electrochemical monitoring of spheroid viability simultaneously. The platform allows for mimicking the complex three-dimensional cellular networks and multicellular characteristics of real solid tumors in vitro, which will be highly useful for high-throughput anticancer drug screening.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Electrochemical sensors and biosensors · Supramolecular Self-Assembly in Materials

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Affiliations

School of Integrative Engineering Chung‐Ang University Seoul 06974 Republic of Korea

Department of Biomedical Engineering SKKU Institute for Convergence Sungkyunkwan University (SKKU) Suwon 16419 Republic of Korea

Department of Chemical and Biological Engineering Hong Kong University of Science and Technology Kowloon Hong Kong 999077 China

Integrative Research Center for Two‐Dimensional Functional Materials Institute of Interdisciplinary Convergence Research Chung‐Ang University Seoul 06974 Republic of Korea

References

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