journal article·2020-11Open access

Photoimmunotherapy: Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth (Small 46/2020)

Rongtao Huang, Zhaoyang Ding, Bang‐Ping Jiang, Zilan Luo, Ting Chen, Zhengxi Guo, Shi‐Chen Ji, Hong Liang, Xing‐Can Shen

Small· Volume 16· Issue 46

Abstract

In article number 2004345, Bang-Ping Jiang, Xing-Can Shen, and co-workers develop one type of brand-new artificial metalloprotein nanoanalogues for enhanced photoimmunotherapy via reasonably integrating “phototherapy-enzymatic” RuO2 and model antigen ovalbumin. This ushers a prospect of concurrently enhancing photodynamic therapy and reversing the immunosuppressive tumor microenvironment by in situ catalyzing overexpressed H2O2 to produce O2.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Click Chemistry and Applications · Photodynamic Therapy Research Studies

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Affiliations

State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources School of Chemistry and Pharmaceutical Science Guangxi Normal University Guilin 541004 P. R. China

References

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