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journal article·2020-11Open access

Tumor Targeting: A Strategy for Tumor Targeting by Higher‐Order Glycan Pattern Recognition: Synthesis and In Vitro and In Vivo Properties of Glycoalbumins Conjugated with Four Different N‐Glycan Molecules (Small 46/2020)

Ivan Smirnov, Regina Sibgatullina, Sayaka Urano, Tsuyoshi Tahara, Peni Ahmadi, Yasuyoshi Watanabe, Ambara R. Pradipta, Almira Kurbangalieva, Katsunori Tanaka

Small· Volume 16· Issue 46
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Source abstract

Abstract

In article number 2004831, Almira Kurbangalieva, Katsunori Tanaka, and co-workers successfully apply the glycan pattern recognition mechanisms for developing a promising cancer targeting strategy in both cell- and mouse-based experiments. The use of the very fast, selective and effective RIKEN click reaction allows to synthesize and screen various structurally well-defined glycoalbumins containing four different N-glycan structures in a very short time, as novel diagnostic, prophylactic, and therapeutic agents.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Glycosylation and Glycoproteins Research · Carbohydrate Chemistry and Synthesis

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Affiliations

Biofunctional Chemistry Laboratory Alexander Butlerov Institute of Chemistry Kazan Federal University 18 Kremlyovskaya street Kazan 420008 Russia

Biofunctional Synthetic Chemistry Laboratory RIKEN Cluster for Pioneering Research 2‐1 Hirosawa Wako Saitama 351‐0198 Japan

RIKEN Center for Biosystems Dynamics Research 6‐7‐3 Minatojima‐minamimachi, Chuo‐ku Kobe Hyogo 650‐0047 Japan

Department of Chemical Science and Engineering School of Materials and Chemical Technology 2‐12‐1 Ookayama, Meguro‐ku Tokyo 152‐8552 Japan

GlycoTargeting Research Laboratory RIKEN Baton Zone Program 2‐1 Hirosawa Wako Saitama 351‐0198 Japan

References

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