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journal article·2020-05Open access

Nanoparticle Interactions: Mass Cytometry and Single‐Cell RNA‐seq Profiling of the Heterogeneity in Human Peripheral Blood Mononuclear Cells Interacting with Silver Nanoparticles (Small 21/2020)

My Kieu Ha, Sook Jin Kwon, Jang‐Sik Choi, Nguyen Thanh Nguyen, Jaewoo Song, Yangsoon Lee, Young‐Eun Kim, Incheol Shin, Jin‐Wu Nam, Tae Hyun Yoon

Small· Volume 16· Issue 21
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Source abstract

Abstract

In article number 1907674, Tae Hyun Yoon and co-workers report complementary use of single-cell based mass cytometry and RNA-seq techniques for the analysis of the heterogeneous interaction between nanoparticles and human immune cells at a single-cell level, via the identification of various immune cell types, quantification of cell-associated nanoparticles, and observation of the changes in transcriptomic profiles and signaling protein expressions.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Single-cell and spatial transcriptomics · Nanoparticles: synthesis and applications

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Affiliations

Center for Next Generation Cytometry Hanyang University Seoul 04763 Republic of Korea

Department of Chemistry College of Natural Sciences Hanyang University Seoul 04763 Republic of Korea

Institute of Next Generation Material Design Hanyang University Seoul 04763 Republic of Korea

Department of Laboratory Medicine College of Medicine Yonsei University Seoul 03722 Republic of Korea

Department of Laboratory Medicine College of Medicine Hanyang University Seoul 04763 Republic of Korea

Department of Life Science College of Natural Sciences Hanyang University Seoul 04763 Republic of Korea

References

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