journal article·2020-05Open access

Endometriosis Treatment: Nanoparticle‐Based Platform for Activatable Fluorescence Imaging and Photothermal Ablation of Endometriosis (Small 18/2020)

Abraham S. Moses, Olena R. Taratula, Hyelim Lee, Fangzhou Luo, Tanner Grenz, Tetiana Korzun, Anna St Lorenz, Fahad Y. Sabei, Shay Bracha, Adam W. G. Alani, Ov D. Slayden, Oleh Taratula

Small· Volume 16· Issue 18

Abstract

In article number 1906936, Ov D. Slayden, Oleh Taratula, and co-workers present a nanomedicine approach for endometriosis treatment. Photo-responsive nanoparticles concurrently delineate and ablate endometriosis tissue xenografts in mice employing real-time fluorescence imaging and photothermal therapy. Following intravenous injection, nanoparticles activate their fluorescence in endometriotic lesions. Excitation by near-infrared light produces heat within endometriotic tissues, resulting in their complete eradication. This approach could aid surgeons in identifying and eliminating endometriosis.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Endometriosis Research and Treatment · Nanocluster Synthesis and Applications

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Affiliations

College of Pharmacy Oregon State University 2730 SW Moody Avenue Portland OR 97201 USA

Division of Reproductive and Developmental Sciences Oregon National Primate Research Center Oregon Health & Science University 505 NW 185th Avenue Beaverton OR 97006 USA

Carlson College of Veterinary Medicine Oregon State University 700 SW 30th Street Corvallis OR 97331 USA

References

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