journal article·2020-05Open access

Nuclear Mechanics: Nuclear Mechanics within Intact Cells Is Regulated by Cytoskeletal Network and Internal Nanostructures (Small 18/2020)

Jitao Zhang, Farid Alisafaei, Miloš Nikolić, Xuefei A. Nou, Hanyoup Kim, Vivek B. Shenoy, Giuliano Scarcelli

Small· Volume 16· Issue 18

Abstract

In article number 1907688, Vivek B. Shenoy, Giuliano Scarcelli, and co-workers use all-optical Brillouin microscopy and 3D chemomechanical modeling to investigate the regulation of nuclear mechanics. It is observed that the nuclear modulus can be modulated by both epigenetic regulation targeting internal nanostructures and cytoskeletal behavior through a robust mechanism conserved in different culturing conditions.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Mitochondrial Function and Pathology

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Affiliations

Fischell Department of Bioengineering University of Maryland College Park MD 20742 USA

Department of Materials Science and Engineering School of Engineering and Applied Science University of Pennsylvania Philadelphia PA 19104 USA

Center for Engineering Mechanobiology University of Pennsylvania Philadelphia PA 19104 USA

Maryland Biophysics Program University of Maryland College Park MD 20742 USA

Canon U.S. Life Sciences, Inc. 9800 Medical Center Drive, Suite C‐120 Rockville MD 20850 USA

References

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