DataVXSmallPaper
journal article·2020-01

Protein‐Based Therapies: Functional Nanocomplexes with Vascular Endothelial Growth Factor A/C Isoforms Improve Collateral Circulation and Cardiac Function (Small 4/2020)

Bokang Qiao, Jing‐Jun Nie, Yihui Shao, Yulin Li, Congcong Zhang, Wenjing Hao, Sijin Li, Dafu Chen, Bingran Yu, Hui‐Hua Li, Fu‐Jian Xu, Jie Du

Small· Volume 16· Issue 4
Publisher page
Source abstract

Abstract

In article number 1905925, Hui-Hua Li, Fu-Jian Xu, Jie Du, and co-workers use a crosslinked heparin polysaccharide nanoparticle to coordinate delivery of vascular endothelial growth factor A/C (VEGF-A/C) isoforms to improve cardiac function via intravenous injection at a dose ratio of 3:1 (VEGF-C vs VEGF-A). Excellent recovery of cardiac function is successfully demonstrated through improving collateral circulation.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Tissue Engineering and Regenerative Medicine · Cardiac and Coronary Surgery Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Remodeling‐Related Cardiovascular Diseases (Ministry of Education) Beijing Institute of Heart Lung, and Blood Vessel Diseases Beijing Anzhen Hospital Affiliated to Capital Medical University Beijing 100029 China

Key Lab of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology) Ministry of Education Beijing Laboratory of Biomedical Materials Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Beijing 100029 China

Department of Nuclear Medicine First Hospital of Shanxi Medical University Taiyuan 030001 China

Laboratory of Bone Tissue Engineering Beijing Laboratory of Biomedical Materials Beijing Research Institute of Orthopaedics and Traumatology Beijing Jishuitan Hospital Beijing 100035 China

Department of Cardiology Institute of Cardiovascular Diseases First Affiliated Hospital of Dalian Medical University Dalian 116011 China

References

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