DataVXSmallPaper
journal article·2019-11Open access

Tumor Imaging: Preferential Tumor Accumulation of Polyglycerol Functionalized Nanodiamond Conjugated with Cyanine Dye Leading to Near‐Infrared Fluorescence In Vivo Tumor Imaging (Small 48/2019)

Fumi Yoshino, Tsukuru Amano, Yajuan Zou, Jian Xu, Fuminori Kimura, Yoshio Furusho, Tokuhiro Chano, Takashi Murakami, Li Zhao, Naoki Komatsu

Small· Volume 15· Issue 48
Publisher pageOpen full text
Source abstract

Abstract

In article number 1901930, Li Zhao, Naoki Komatsu, and co-workers functionalize nanodiamonds with polyglycerol and cyanine dye, effectively shielding protein adsorption in the blood stream, and prolonging in vivo circulation significantly. As a result, only the tumor is clearly imaged by near-infrared fluorescence from the nanodiamonds due to their preferential accumulation in tumor rather than the organs such as the liver and spleen.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Obstetrics and Gynecology Shiga University of Medical Science Seta Otsu 520‐2192 Japan

Graduate School of Human and Environmental Studies Kyoto University Sakyo‐ku Kyoto 606‐8501 Japan

Department of Chemistry Shiga University of Medical Science Seta Otsu 520‐2192 Japan

Department of Clinical Laboratory Medicine Shiga University of Medical Science Seta Otsu 520‐2192 Japan

State Key Laboratory of Radiation Medicine and Protection School of Radiation Medicine and Protection & School for Radiological and Interdisciplinary Sciences (RAD‐X) Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions Soochow University Suzhou Jiangsu 215123 China

References

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