journal article·2019-07Open access

Antithrombotic Therapies: Near‐Infrared Light Activated Thermosensitive Ion Channel to Remotely Control Transgene System for Thrombolysis Therapy (Small 27/2019)

Da Zhang, Cuilin Zhang, Shanyou Lan, Yanbing Huang, Jingfeng Liu, Juan Li, Xiaolong Liu, Huanghao Yang

Small· Volume 15· Issue 27

Abstract

In article number 1901176, Juan Li, Xiaolong Liu, Huanghao Yang, and co-workers develop a thrombolysis approach for noninvasive, on-demand and sustained antithrombotic therapy with bioengineered cells, which could be noninvasively and precisely controlled to produce urokinase plasminogen activator (uPA) in situ via an NIR laser to significantly enhance the thrombolysis therapeutic effects by spatiotemporally controlling the local temperature.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Extracellular vesicles in disease · Advanced Nanomaterials in Catalysis

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Affiliations

MOE Key Laboratory for Analytical Science of Food Safety and Biology Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety State Key Laboratory of Photocatalysis on Energy and Environment College of Chemistry Fuzhou University Fuzhou 350116 P. R. China

The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province Mengchao Hepatobiliary Hospital of Fujian Medical University Fuzhou 350025 P. R. China

Institute of Molecular Medicine Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200240 P. R. China

References

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