journal article·2019-05Open access

Cells at Wrinkled Interfaces: Laser‐Assisted Strain Engineering of Thin Elastomer Films to Form Variable Wavy Substrates for Cell Culture (Small 21/2019)

Caterina Tomba, Tatiana Petithory, Riccardo Pedron, Aissam Airoudj, Ilaria Di Meglio, Aurélien Roux, Valeriy Luchnikov

Small· Volume 15· Issue 21

Abstract

In article number 1900162, Caterina Tomba, Valeriy Luchnikov, and co-workers present a versatile approach to produce curved surfaces with dynamic and variable topographic parameters. Mid-infrared laser exposure allows for surface stiffening of an elastomer that is suitable as wavy substrate to grow cells on smooth and more realistic micro-environments. The wrinkled geometry is tuned by controlling the shape and stretching rate of the substrate and the irradiation parameters of the laser. This technique is easily accessible for further studies on cell migration and cell fate determination.
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Research context

OpenAlex topics: Advanced Materials and Mechanics

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Affiliations

Department of Biochemistry University of Geneva Quai Ernest Ansermet 30 CH‐1211 Geneva Switzerland

Université de Haute‐Alsace CNRS, IS2M UMR 7361, 15, Rue Jean Starcky F‐68100 Mulhouse France

Faculty of Pharmacy University of Strasbourg CNRS UMR 7199Laboratoire de conception et application de molécules bioactives (CAMB) équipe de Pharmacie Biogalénique 74 Route du Rhin 67401 Ilkirch Cedex France

National Center of Competence in Research Chemical Biology University of Geneva Quai Ernest Ansermet 30 CH‐1211 Geneva Switzerland

References

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