Nanopore Sensing: Enhanced Sensitivity in Nanopore Sensing of Cancer Biomarkers in Human Blood via Click Chemistry (Small 2/2019)
Source abstract
Abstract
In article number 1804078, Hai-Chen Wu and co-workers develop a strategy for the ultrasensitive detection of cancer biomarkers based on the combination of a sandwich assay, “click” chemistry, and DNA-assisted nanopore sensing. The limit of detection of the strategy can be as low as the femtomolar level. Furthermore, it can effectively eliminate interferences from plasma proteins and be applied in the clinical detection of cancer biomarkers.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanopore and Nanochannel Transport Studies · Microfluidic and Capillary Electrophoresis Applications · Microfluidic and Bio-sensing Technologies
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Affiliations
Institute for Advanced Study Chengdu University Chengdu 610052 China
Beijing National Laboratory for Molecular Sciences Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China
Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety Multidisciplinary Center Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China
References
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