Protein Coronas: Beyond Global Charge: Role of Amine Bulkiness and Protein Fingerprint on Nanoparticle–Cell Interaction (Small 46/2018)
Source abstract
Abstract
Nanoparticle surface chemistry is a key component for nanoparticle-cell interactions. Positively charged amines are hypothesized to drive these via Coulombic interactions with a negatively charged cell membrane. In article number 1802088, Calum Kinnear, Thomas L. Moore, Alke Petri-Fink, and co-workers report that the degree of amine methylation (i.e. amine bulkiness) is critical in mediating the nanoparticle-cell interaction via the protein corona.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Cancer Research and Treatment · Nanoparticle-Based Drug Delivery · Biological Research and Disease Studies
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Affiliations
Chemistry Department Université de Fribourg 1700 Fribourg Switzerland
Adolphe Merkle Institute Université de Fribourg 1700 Fribourg Switzerland
Department of Biology Université de Fribourg 1700 Fribourg Switzerland
School of Chemistry University of Melbourne Parkville 3010 Australia
References
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