journal article·2018-09Open access

Insulin Delivery Platforms: Multiresponsive Supramolecular Theranostic Nanoplatform Based on Pillar[5]arene and Diphenylboronic Acid Derivatives for Integrated Glucose Sensing and Insulin Delivery (Small 38/2018)

Minzan Zuo, Weirui Qian, Zuqiang Xu, Wei Shao, Xiao‐Yu Hu, Dongmei Zhang, Juli Jiang, Xiaoqiang Sun, Leyong Wang

Small· Volume 14· Issue 38

Abstract

In article number 1801942, Xiao-Yu Hu, Dongmei Zhang, Juli Jiang, Leyong Wang, and co-workers develop a closed–loop insulin delivery platform based on a supramolecular strategy. Insulin can be transported to the blood vessel through this multiple stimuli-responsive system. Under hyperglycemic conditions, the in situ generated H2O2 and acidic microenvironment leads to the efficient release of insulin.
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Research context

OpenAlex topics: Supramolecular Self-Assembly in Materials · Nanoplatforms for cancer theranostics · Luminescence and Fluorescent Materials

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Affiliations

Key Laboratory of Mesoscopic Chemistry of MOE and Collaborative Innovation Center of Chemistry for Life Sciences School of Chemistry and Chemical Engineering Nanjing University Nanjing 210023 China

Applied Chemistry Department School of Material Science & Engineering Nanjing University of Aeronautics & Astronautics Nanjing 210016 China

State Key Laboratory of Pharmaceutical Biotechnology School of Life Science Nanjing University Nanjing 210023 China

School of Petrochemical Engineering Changzhou University Changzhou 213164 China

References

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