journal article·2017-08Open access

Correlative Microscopy: Site‐Specific SERS Assay for Survivin Protein Dimer: From Ensemble Experiments to Correlative Single‐Particle Imaging (Small 32/2017)

Jörg Wissler, Sandra Bäcker, Alessandro Feis, Shirley K. Knauer, Sebastian Schlücker

Small· Volume 13· Issue 32

Abstract

An assay for protein dimers using surface-enhanced Raman scattering (SERS) is presented, in article number 1700802, by Sebastian Schlücker and co-workers. Site-specific binding of the Survivin protein dimer to molecularly functionalized gold nanoparticles results in the formation of protein-bridged dimers of gold nanoparticles. The dimers exhibit the characteristic SERS spectrum of Raman reporter molecules in the hot spot generated upon resonant laser excitation.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Gold and Silver Nanoparticles Synthesis and Applications · Nanoparticle-Based Drug Delivery · Quantum Dots Synthesis And Properties

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Affiliations

Physical Chemistry I Department of Chemistry University of Duisburg‐Essen and Center for Nanointegration Duisburg‐Essen (CENIDE) Universitätsstrasse 5 Essen D‐45141 Germany

Molecular Biology II Department of Biology University Duisburg‐Essen and Zentrum für Molekulare Biotechnologie (ZMB) Universitätsstrasse 5 Essen D‐45141 Germany

Dipartimento di Chimica “Ugo Schiff” Universita' di Firenze Via della Lastruccia 3 Sesto Fiorentino FI I‐50019 Italy

References

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