journal article·2017-03Open access

Magnetic Nanoparticles: High‐Throughput, Protein‐Targeted Biomolecular Detection Using Frequency‐Domain Faraday Rotation Spectroscopy (Small 12/2017)

Richard J. Murdock, Shawn A. Putnam, Soumen Das, Ankur Gupta, Elyse D. Z. Chase, Sudipta Seal

Small· Volume 13· Issue 12

Abstract

In article number 1602862, Shawn A. Putnam and co-workers, revisiting a 170 year old magneto-optical phenomenon, reveal a fast, sensitive, and versatile medical test. Polarized light interacts with functionalized magnetic nanoparticles in the biomolecule characterization method called fd-FRS (frequency-domain Faraday Rotation Spectroscopy). Alternating magnetic fields induce particle rotation and realignment with the magnetic field – a process dependent on the size, conformation, and density of the conjugated biomolecules.
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Research context

OpenAlex topics: Genetics, Bioinformatics, and Biomedical Research · Characterization and Applications of Magnetic Nanoparticles

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Affiliations

Health Sciences and Technology (HST) Institute for Medical Engineering and Science (IMES) Massachusetts Institute of Technology and Harvard University 77 Massachusetts Avenue 76‐679 Cambridge MA 02139 USA

Department of Mechanical and Aerospace Engineering University of Central Florida P.O. Box, 162450, ENGR 1, Rm. 213 Orlando FL 32816 USA

Department of Materials Science and Engineering Advanced Materials Processing and Analysis Center, (AMPAC) Nanoscience Technology Center (NSTC) University of Central Florida P.O. Box 162455, ENGR 1, Rm. 207 Orlando FL 32816 USA

Department of Mechanical Engineering and Applied Mechanics University of Pennsylvania 229, Towne Building, 220 South 33rd Street Philadelphia PA 19104 USA

References

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