journal article·2017-02Open access

RNA Delivery: Modularized Gold Nanocarriers for TAT‐Mediated Delivery of siRNA (Small 8/2017)

Xiao Huang, Yifan Lai, Gary B. Braun, Norbert O. Reich

Small· Volume 13· Issue 8

Abstract

A novel plasmonic gold nanocarrier using a modular RNA scaffold significantly improves delivery efficiency into diverse human cells, as presented by Norbert O. Reich and co-workers in article number 1602473. The orthogonal positioning of cell targeting peptides and functional RNA provides unprecedented control in the delivery of biologically active RNA. NIR light-triggered RNA release with spatio-temporal control further enhances the RNA delivery efficiency.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: RNA Interference and Gene Delivery · Advanced biosensing and bioanalysis techniques · Advanced Nanomaterials in Catalysis

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Affiliations

Department of Chemistry and Biochemistry University of California Santa Barbara CA 93106 USA

Cancer Research Center Sanford‐Burnham Medical Research Institute La Jolla CA 92037 USA

References

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