journal article·2016-10Open access

Nanomaterial Uptake: Fast Targeting and Cancer Cell Uptake of Luminescent Antibody‐Nanozeolite Bioconjugates (Small 39/2016)

Riccardo Marega, Eko Adi Prasetyanto, Carine Michiels, Luisa De Cola, Davide Bonifazi

Small· Volume 12· Issue 39

Abstract

On page 5431, L. De Cola, D. Bonifazi, and co-workers report the fast targeting and cancer cells uptake of nanozeolite/Cetuximab bioconjugates. The effects are depicted on the front cover, which highlights the antibody-dependent and receptor-mediated endocytosis of this luminescent nanomaterial by the cancer cells. This hasty internalization profile can be exploited to reduce the nanomaterial clearance processes occurring in-vivo, which determine unfavourable biodistribution and foster “off-target” activities.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Computational Drug Discovery Methods · Nanoparticle-Based Drug Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Namur Research College (NARC) and Department of Chemistry University of Namur Rue de Bruxelles 61 Namur B‐5000 Belgium

Institut de science et d'Ingénierie Supramoléculaire (ISIS) Université de Strasbourg 8 Rue Gaspard Monge, BP 70028 Strasbourg F‐67000 France

Karlsruher Institut für Technologie KIT‐INT Karlsruhe D‐76131 Germany

Cellular Biology Research Unit – NARILIS University of Namur Rue de Bruxelles 61 Namur B‐5000 Belgium

School of Chemistry Cardiff University Park Place, Cardiff CF10 3AT United Kingdom

References

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