Self‐Assembly: Host–Guest Interaction‐Mediated Construction of Hydrogels and Nanovesicles for Drug Delivery (Small 44/2015)
Source abstract
Abstract
A 1,8-naphthalimide derivative that forms a stable hydrogel with very low critical gelation concentration is reported by Y. Zhao and co-workers. By taking advantage of the host–guest interaction, the complexation of this compound with cucurbit[8]uril leads to the formation of nanovesicles on page 5901. A cytotoxicity assay with cancer cells confirms that doxorubicin-loaded hydrogel and nanovesicles are effectively endocytosed by cancer cells, showing therapeutic effects. This work provides a strategy in the development of multiple drug nanocarriers from amphiphilic assemblies.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Supramolecular Self-Assembly in Materials · Nanoplatforms for cancer theranostics
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Affiliations
Division of Chemistry and Biological Chemistry School of Physical and Mathematical Sciences Nanyang Technological University 21 Nanyang Link Singapore 637371
Division of Theoretical Chemistry and Biology School of Biotechnology KTH Royal Institute of Technology SE‐ 10691 Stockholm Sweden
School of Materials Science and Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798
References
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