journal article·2015-03Open access

Biomaterials: Efficient Encapsulation of Fe3O4 Nanoparticles into Genetically Engineered Hepatitis B Core Virus‐Like Particles Through a Specific Interaction for Potential Bioapplications (Small 9‐10/2015)

Lihua Shen, Jun Zhou, Yixiao Wang, Ning Kang, Xuebin Ke, Shengli Bi, Lei Ren

Small· Volume 11· Issue 9-10

Abstract

A method to encapsulate magnetic nanoparticles into His-tagged virus-like particles (VLPs) is developed by L. Ren and co-workers on page 1190. It is the first report using the affinity of histidine tags for the nickel-nitrilotriacetic acid chelate to trigger encapsulation of nanoparticles by VLPs. This makes it possible to integrate a wide range of starting nanoparticles into fundamentally different kinds of viral coating proteins or other nonenveloped viruses for application in cancer nanotechnology and medicine.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Bacteriophages and microbial interactions

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biomaterials College of Materials Xiamen University Xiamen 361005 P.R. China

Chinese Center for Disease Control & Prevention Institute Viral Disease Control & Prevention Beijing 102206 P.R. China

State Key Laboratory for Physical Chemistry of Solid Surfaces Xiamen University Xiamen 361005 P.R. China

References

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