journal article·2015-09Open access

Drug Delivery: Gold Nanocluster Embedded Albumin Nanoparticles for Two‐Photon Imaging of Cancer Cells Accompanying Drug Delivery (Small 33/2015)

Rumi Khandelia, Satyapriya Bhandari, Uday Narayan Pan, Siddhartha Sankar Ghosh, Arun Chattopadhyay

Small· Volume 11· Issue 33

Abstract

The fabrication of biocompatible gold nanocluster-embedded albumin nanoparticles for potential theranostic applications is reported by A. Chattopadhyay and co-workers on page 4075. Anti-cancer drug doxorubicin-loaded nanoparticles are internalized by cervical cancer HeLa cells in vitro, leading to apoptotic cell death. Simultaneously, imaging can be achieved by using one- and two-photon excitation, with the two-photon excitation/emission wavelengths lying in the biological window of 650–900 nm. The luminescent nanoparticles may serve as model platforms for theranostics.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Nanocluster Synthesis and Applications · Nanoparticle-Based Drug Delivery

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Affiliations

Department of Chemistry Indian Institute of Technology Guwahati Guwahati 781039 India

Department of Biosciences and Bioengineering Centre for Nanotechnology Indian Institute of Technology Guwahati Guwahati 781039 India

Department of Chemistry Centre for Nanotechnology Indian Institute of Technology Guwahati Guwahati 781039 India

References

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