Gene Delivery: Artificial Cell Membrane‐Mimicking Nanostructure Facilitates Efficient Gene Delivery through Fusogenic Interaction with the Plasma Membrane of Living Cells (Small 21/2011)

The image shows a cell-membranemimicking nanostructure, which possesses amphipathic properties arising from the presence of hydrophobic alkyl chains and polar phosphorylcholine (PC) groups in the self-assembled structure. The distance between nanostructured multilayers is 4.5 nm, which resembles such distances in natural cell membranes. The self-assembled nanostructure has a strong affinity toward natural cell membranes and, thus, preloaded gene complexes are delivered into cells through a fusogenic process with a cellular membrane