Sensors: Electrokinetic Preconcentration of Small Molecules Within Volumetric Electromagnetic Hotspots in Surface Enhanced Raman Scattering (Small 21/2015)

Surface-enhanced Raman scattering (SERS) extensively stimulates nanotechnology researchers as a multidisciplinary topic. The inside cover illustrates how the electrokinetic preconcentration actively concentrates charged biochemical species into the volumetric electromagnetic hotspots of nanogap-rich silver nanoislands on glass nanopillar arrays, by applying an electric field for SERS. On page 2487, this pioneering work presented by K.-H. Jeong and co-workers successfully demonstrates label-free fingerprinting of 1 pM dye or serotonin neurotransmitter at the nanomolar level.