DataVXSmallPaper
journal article·2023-10Open access

Simultaneous Delivery of Doxorubicin and EZH2‐Targeting siRNA by Vortex Magnetic Nanorods Synergistically Improved Anti‐Tumor Efficacy in Triple‐Negative Breast Cancer (Small 43/2023)

Yunshu Lu, Fenfen Gu, Yuwei Ma, Ruonan Li, Yi Luo, Xianhong Da, Lan Jiang, Xiang Li, Yan Liu

Small· Volume 19· Issue 43
Publisher pageOpen full text
Source abstract

Abstract

Nanomedicine In article number 2301307, Yan Liu, Xiang Li, and co-workers report a novel engineered magnetic nanodrug based on Fe3O4 vortex nanorods coated with a macrophage membrane loaded with doxorubicin and EZH2 siRNA. This novel nanodrug has synergistic activity chemotherapy and gene therapy, which shows promising clinical application potential in triple-negative breast cancer (TNBC) therapy.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Extracellular vesicles in disease

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Breast Surgery Xinhua Hospital Affiliated to Shanghai Jiao Tong University School<?brk?> of Medicine Shanghai 200092 P. R. China

Department of Clinical Pharmacy Xinhua Hospital Affiliated to Shanghai Jiao Tong University School<?brk?> of Medicine Shanghai 200092 P. R. China

School of Materials and Chemistry University of Shanghai for Science and Technology Shanghai 200093 P. R. China

Biotheus Inc. Guangdong Province Zhuhai 519080 P. R. China

Clinical Pharmacy Innovation Institute Shanghai Jiao Tong University School of Medicine Shanghai 200092 P. R. China <?vsp 90pt?>

References

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