journal article·2023-07Open access

Direct Thermal Growth of Gold Nanopearls on 3D Interweaved Hydrophobic Fibers as Ultrasensitive Portable SERS Substrates for Clinical Applications (Small 28/2023)

Hsin‐Yao Lin, Wan‐Ru Chen, Li‐Chia Lu, Hsuen‐Li Chen, Yu‐Hsuan Chen, Michael Pan, Chi‐chia Chen, Chihchen Chen, Tzung‐Hai Yen, Dehui Wan

Small· Volume 19· Issue 28

Abstract

Gold Nanopearls In article number 2207404, Chihchen Chen, Tzung-Hai Yen, Dehui Wan, and co-workers develop a paper-based, portable surface-enhanced Raman spectroscopy (SERS) detection platform with an extremely high Raman enhancement factor and detectability at sub-femtomolar concentrations, even when operated with a portable NIR Raman spectrometer. The fabrication process involves depositing abundant and dense gold nanopearls with narrow gap distances directly onto fluorosilane-modified cellulose fibers through simple thermal evaporation. This scalable and portable fibrous SERS substrate has the potential for practical on-site detection in biofluid analysis, point-of-care diagnostics, and precision medicine.
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Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis

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Affiliations

Institute of Biomedical Engineering and Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu 30010 Taiwan

Institute of Nanoengineering and Microsystems National Tsing Hua University Hsinchu 30010 Taiwan

Division of Neurosurgery, Department of Surgery MacKay Memorial Hospital 10449 Taipei Taiwan

Department of Materials Science and Engineering and Center of Atomic Initiative for New Materials (AI‐MAT) National Taiwan University Taipei 10617 Taiwan

Department of Power Mechanical Engineering National Tsing Hua University Hsinchu 30010 Taiwan

College of Medicine Chang Gung University Taoyuan 33378 Taiwan

References

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