journal article·2023-05Open access

Precision Delivery of Dual Immune Inhibitors Loaded Nanomodulator to Reverse Immune Suppression for Combinational Photothermal‐Immunotherapy (Small 21/2023)

Ying Tian, Muhammad Rizwan Younis, Yatong Zhao, Kai Guo, Jiayingzi Wu, Longjiang Zhang, Peng Huang, Zhongqiu Wang

Small· Volume 19· Issue 21

Abstract

Combinational Photothermal-Immunotherapy In article number 2206441, Longjiang Zhang, Peng Huang, Zhongqiu Wang, and co-workers load dual-immune inhibitors nanomodulators for combinational photothermal-immunotherapy through regulating abnormal enzymatic metabolism of IDO, blocking PD-L1/PD-1 and CD47/SIRPα to reverse immunosuppressive tumor microenvironment, and prevent tumor growth and re-challenge.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Cancer Immunotherapy and Biomarkers · Immune cells in cancer

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Radiology Affiliated Hospital of Nanjing University of Chinese Medicine Nanjing Jiangsu 210029 P. R. China

Marshall Laboratory of Biomedical Engineering International Cancer Center Laboratory of Evolutionary Theranostics (LET) School of Biomedical Engineering Shenzhen University Health Science Center Shenzhen Guangdong 518060 P. R. China

Department of Medical Imaging Jinling Hospital School of Medicine Nanjing University Nanjing Jiangsu 210002 P. R. China

References

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