DataVXSmallPaper
journal article·2022-12Open access

Cell Membrane‐Anchoring Nano‐Photosensitizer for Light‐Controlled Calcium‐Overload and Tumor‐Specific Synergistic Therapy (Small 48/2022)

Min Gao, Tianhao Yang, Weiji Qin, Qian Wang, Mingyue Huang, Hui Peng, Meng Shao, Wanqing Yao, Xiaoqing Yi, Gengyun Sun, Xiaoyan He

Small· Volume 18· Issue 48
Publisher pageOpen full text
Source abstract

Abstract

Tumor Therapy In article number 2204689, Xiaoqing Yi, Gengyun Sun, Xiaoyan He, and co-workers develop a cell membrane-anchoring nano-photosensitizer (CMA-nPS) based on genetically engineered cellular membrane vesicles. The nano-photosensitizer significantly induces intercellular Ca2+ overload through multistage endogenous homeostasis disruption under laser irradiation. With an obvious synergistic ablative effect on tumor cells, this strategy can be a promising candidate for tumor therapy.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Extracellular vesicles in disease

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Respiratory and Critical Care Medicine The First Affiliated Hospital of Anhui Medical University Hefei 230022 China

School of Life Sciences Anhui Medical University Hefei 230032 China

Anhui Province Key Laboratory of Measuring Theory and Precision Instrument School of Instrument Science and Optoelectronics Engineering Hefei University of Technology Hefei 230009 China

Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases Ministry of Education Gannan Medical University Ganzhou 341000 China

Department of Orthopedics The Fourth Affiliated Hospital of Anhui Medical University Hefei Anhui 230012 China

References

Reference metadata was not supplied for this record.