Human Heart Anoxia and Reperfusion Tissue (HEART) Model for the Rapid Study of Exosome Bound miRNA Expression As Biomarkers for Myocardial Infarction (Small 28/2022)
Source abstract
Abstract
Myocardial Infarction Diagnosis To address the limitations of current myocardial infarction (MI) detection technology, in article 2201330, Pinar Zorlutuna and co-workers develop the human heart anoxia and reperfusion tissue (HEART) model combined with a near real-time microRNAs (miRNAs) concentration sensor for analysis of miRNAs under MI conditions. This model provides a modular, physiologically relevant tool for the discovery of novel MI biomarkers as well as novel diagnostic and therapeutic approaches.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: MicroRNA in disease regulation · Extracellular vesicles in disease · Cardiovascular Disease and Adiposity
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Bioengineering Graduate Program University of Notre Dame Notre Dame IN 46556 USA
Department of Aerospace and Mechanical Engineering University of Notre Dame Notre Dame IN 46556 USA
Department of Chemical and Biomolecular Engineering University of Notre Dame Notre Dame IN 46556 USA
Division of Cardiology Department of Medicine in the College of Medicine University of Florida Gainesville FL 32610 USA
References
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