DataVXSmallPaper
journal article·2022-06

Combination of Metal‐Phenolic Network‐Based Immunoactive Nanoparticles and Bipolar Irreversible Electroporation for Effective Cancer Immunotherapy (Small 25/2022)

Jun‐Hyeok Han, Ha Eun Shin, Jiyoung Lee, Jeon Min Kang, Jung‐Hoon Park, Chun Gwon Park, Dong Keun Han, Ik‐Hwan Kim, Wooram Park

Small· Volume 18· Issue 25
Publisher page
Source abstract

Abstract

Cancer Immunotherapy In article number 2200316, Dong Keun Han, Ik-Hwan Kim, Wooram Park, and co-workers present a combination therapy of metal-phenolic network-based immunoactive nanoparticles and bipolar irreversible electroporation (IRE) technology. A CpG-oligodeoxynucleotides (CpG-ODNs)-coated Mn-phenolic network nanoparticle efficiently primes antigen-presenting cells to M1 polarization and proinflammatory cytokine production. The bipolar IRE efficiently induces immunogenic cell death. This combinational therapy will be a new tool for effective cancer immunotherapy.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Microbial Inactivation Methods · Molecular Communication and Nanonetworks

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Integrative Biotechnology College of Biotechnology and Bioengineering Sungkyunkwan University Seoburo 2066 Suwon Gyeonggi 16419 Republic of Korea

Department of Biotechnology College of Life Sciences and Biotechnology Korea University Seoul 02841 Republic of Korea

Institute of Pharmaceutics College of Pharmaceutical Sciences Zhejiang University Hangzhou Zhejiang 310058 People's Republic of China

Biomedical Engineering Research Center Asan Institute for Life Sciences Asan Medical Center, 88 Olympic‐ro 43‐gil, Songpa‐gu Seoul 05505 Republic of Korea

Department of Biomedical Engineering SKKU Institute for Convergence Sungkyunkwan University Suwon Gyeonggi 16419 Republic of Korea

Department of Intelligent Precision Healthcare Convergence SKKU Institute for Convergence Sungkyunkwan University Suwon Gyeonggi 16419 Republic of Korea

Department of Biomedical Science College of Life Sciences CHA University 335 Pangyo‐ro, Bundang‐gu Seongnam Gyeonggi 13488 Republic of Korea

References

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