journal article·2022-03

Bicyclol Alleviates Atherosclerosis by Manipulating Gut Microbiota (Small 9/2022)

Xiao‐Lin Li, Jin‐Jin Cui, Wen‐Sheng Zheng, Jin‐Lan Zhang, Rui Li, Xiao‐Lei Ma, Miao Lin, Hui‐Hui Guo, Cong Li, Xiao‐You Yu, Peng Du, Li‐Min Zhao, Shuwang He, Pei Lan, Jian‐Dong Jiang, Yongsheng Che, Lu‐Lu Wang

Small· Volume 18· Issue 9
Publisher page

Abstract

Atherosclerosis Treatment Herb derived drugs modulate gut microbiome homeostasis and gut-generated bio-metabolites. In article number 2105021, Jian-Dong Jiang, Yongsheng Che, Lu-Lu Wang, and co-workers modify the immune cell dynamics and liver function using herb-derived bicyclol, leading to improved chronic inflammation and cholesterol metabolism. The endothelial activation and cholesterol ester accumulation in the aortic arch are ameliorated causing less plaque onset.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Lipid metabolism and disorders · Gut microbiota and health

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia Medica Chinese Academy of Medical Science and Peking Union Medical College Beijing 100050 China

Institute of Medicinal Biotechnology Chinese Academy of Medical Science and Peking Union Medical College Beijing 100050 China

College of Pharmacy Shandong University Beijing 250012 China

References

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