journal article·2021-10Open access

Remodeling of Tumor Microenvironment by Tumor‐Targeting Nanozymes Enhances Immune Activation of CAR T Cells for Combination Therapy (Small 43/2021)

Lipeng Zhu, Jie Liu, Guangyu Zhou, Tzu‐Ming Liu, Yunlu Dai, Guangjun Nie, Qi Zhao

Small· Volume 17· Issue 43

Abstract

Tumor-Targeting Nanozymes In article number 2102624, Qi Zhao and co-workers demonstrate that a nanozyme-mediated photothermal-nanocatalytic effect disrupts the tumor extracellular matrix and induces cancer cell death. The alterations in the tumor microenvironment ultimately promote tumor infiltration and immune response of CAR T cells against solid tumors.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Immune cells in cancer

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Affiliations

Cancer Centre Institute of Translational Medicine Faculty of Health Sciences University of Macau Macau SAR 999078 China

MoE Frontiers Science Center for Precision Oncology University of Macau Macau SAR 999078 China

CAS Key Laboratory for Biomedical Effects of Nanomaterials & Nanosafety National Center for Nanoscience and Technology Beijing 100190 China

References

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