Nanobody‐Engineered Natural Killer Cell Conjugates for Solid Tumor Adoptive Immunotherapy (Small 45/2021)
Source abstract
Abstract
Nanobody-Natural Killer Cell Conjugates In article number 2103463, Zhimeng Wu, Zhaohui Huang, and co-workers construct a nanobody-NK92MI cell conjugate through natural killer (NK) cell surface metabolic glycoengineering and biocompatible copper free click chemistry for solid tumor adoptive immunotherapy. The nanobody-engineered NK cell conjugates gain excellent cancer tissue penetration capability and exhibit improved therapeutic efficacy in a solid tumor mouse model.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: CAR-T cell therapy research · Immune Cell Function and Interaction
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Affiliations
Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of Education School of Biotechnology Jiangnan University Wuxi Jiangsu 214122 P. R. China
Wuxi Cancer Institute Affiliated Hospital of Jiangnan University Wuxi Jiangsu 214062 P. R. China
Institute of Translational Medicine Jiangnan University Wuxi Jiangsu 214122 P. R. China
Laboratory of Cancer Epigenetics Jiangnan University Wuxi Jiangsu 214122 P. R. China
References
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