Antibiotic Resistance: Microfluidic Evolution‐On‐A‐Chip Reveals New Mutations that Cause Antibiotic Resistance (Small 10/2021)
Source abstract
Abstract
Microfluidics reveals ambiguous antibiotic resistance scenarios. A custom microfluidic device reported by Kersten S. Rabe and co-workers (article number 2007166) elucidates for the first time how bacteria turn into either resistant or persistent “superbugs” due to varying antibiotic exposure. The chip accelerates evolution, leading to the discovery of previously unknown resistance mutations within hours, paving the way for a better understanding of the mechanisms of resistance.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Innovative Microfluidic and Catalytic Techniques Innovation · Antibiotic Use and Resistance
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute for Biological Interfaces 1 (IBG‐1) Karlsruhe Institute of Technology (KIT) Hermann‐von‐Helmholtz‐Platz 1 Eggenstein‐Leopoldshafen 76344 Germany
Department of Genetics and Cytology National Research Centre (NRC) 33 El Buhouth St. Cairo 12622 Egypt
References
Reference metadata was not supplied for this record.