journal article·2020-09Open access

Bioimaging: Surface Charge of Supramolecular Nanosystems for In Vivo Biodistribution: A MicroSPECT/CT Imaging Study (Small 37/2020)

Ling Ding, Zhenbin Lyu, Beatrice Louis, Aura Tintaru, Erik Laurini, Domenico Marson, Mengjie Zhang, Wanxuan Shao, Yifan Jiang, Ahlem Bouhlel, Laure Balasse, Philippe Garrigue, Eric Mas, Suzanne Giorgio, Juan Iovanna, Yuanyu Huang, Sabrina Pricl, Benjamin Guillet, Ling Peng

Small· Volume 16· Issue 37

Abstract

In article number 2003290, Ling Peng and co-workers report a self-assembling supramolecular dendrimer probe for tumor imaging by single photon emission computed tomography (SPECT). Altering the radionuclide chelators on the dendrimer surface leads to a highly favorable biodistribution profile with a drastically reduced uptake in liver and a significantly improved tumor imaging contrast.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Dendrimers and Hyperbranched Polymers · Nanoplatforms for cancer theranostics

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Affiliations

Aix‐Marseille Université CNRS Centre Interdisciplinaire de Nanoscience de Marseille (CINaM), UMR 7325 Equipe Labellisée Ligue Contre le Cancer Marseille 13288 France

Aix‐Marseille Université CNRS Centre de Résonance Magnétique Biologique et Médicale (CRMBM), UMR 7339 Marseille 13385 France

Aix Marseille Univ CNRS Institut de Chimie Radicalaire, UMR 7273 Marseille 13013 France

Aix‐Marseille Université INSERM INRAE, C2VN Marseille 13005 France

Aix‐Marseille Université CNRS CERIMED Marseille 13005 France

Molecular Biology and Nanotechnology Laboratory (MolBNL@UniTS) DEA University of Trieste Trieste 34127 Italy

School of Life Science Advanced Research Institute of Multidisciplinary Science Institute of Engineering Medicine Key Laboratory of Molecular Medicine and Biotherapy Beijing Institute of Technology Beijing 100081 China

Aix‐Marseille Université INSERM CNRS, Institut Paoli‐Calmettes Centre de Recherche en Cancérologie de Marseille (CRCM) Marseille 13288 France

Department of General Biophysics Faculty of Biology and Environmental Protection University of Lodz Lodz 90‐236 Poland

References

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