Tumor Margin Demarcation and Therapy: A NanoFlare‐Based Strategy for In Situ Tumor Margin Demarcation and Neoadjuvant Gene/Photothermal Therapy (Small 50/2018)

Rong Yan; Jie Chen; Jianhao Wang; Jiaming Rao; Xuancheng Du; Yongming Liu; Leshuai Zhang; Lin Qiu; Bo Liu; Yuan‐Di Zhao; Pengju Jiang; Chunying Chen; Yong‐Qiang Li

doi:10.1002/smll.201870245

journal article·2018-12Open access

Tumor Margin Demarcation and Therapy: A NanoFlare‐Based Strategy for In Situ Tumor Margin Demarcation and Neoadjuvant Gene/Photothermal Therapy (Small 50/2018)

Rong Yan, Jie Chen, Jianhao Wang, Jiaming Rao, Xuancheng Du, Yongming Liu, Leshuai Zhang, Lin Qiu, Bo Liu, Yuan‐Di Zhao, Pengju Jiang, Chunying Chen, Yong‐Qiang Li

Small· Volume 14· Issue 50

Publisher page Open full text

Source abstract

Abstract

In article number 1802745, Yong-Qiang Li and co-workers report a robust tumor microenvironment-responsive theranostic nanoprobe (NanoFlare). By virtue of its anisotropic oligonucleotides-spike nanostructure, the NanoFlare can enter tumor cells universally regardless of cell type and produce a redox-activated fluorescence signal. The NanoFlare enables accurate intraoperative margin demarcation of different tumors and efficient gene/photothermal neoadjuvant therapy in vivo.

Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Advanced biosensing and bioanalysis techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Radiation Medicine and Protection School of Radiation Medicine and Protection Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions Soochow University Suzhou 215123 China

Suzhou Hospital Affiliated to Nanjing Medical University Suzhou 215002 China

School of Pharmaceutical Engineering and Life Science Changzhou University Changzhou 213164 China

Britton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Wuhan 430074 China

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology of China Beijing 100190 China

References

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