journal article·2018-10Open access

Microgels: SERS‐Active‐Charged Microgels for Size‐ and Charge‐Selective Molecular Analysis of Complex Biological Samples (Small 40/2018)

Dong Jae Kim, Sung‐Gyu Park, Dong‐Ho Kim, Shin‐Hyun Kim

Small· Volume 14· Issue 40

Abstract

In article number 1802520, Dong-Ho Kim, Shin-Hyun Kim, and co-workers design charged microgels to encapsulate agglomerates of gold nanoparticles for the direct analysis of biological samples through Raman analysis. The charged microgels concentrate oppositely charged small molecules while excluding large proteins, increasing Raman intensity and preventing gold contamination. Using the microgels, fipronil sulfone, a metabolite of a toxic insecticide dissolved in eggs, is directly detected without any sample pretreatment.
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Research context

OpenAlex topics: Spectroscopy Techniques in Biomedical and Chemical Research

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Affiliations

Department of Chemical and Biomolecular Engineering (BK21+ Program) Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 South Korea

Advanced Nano‐Surface Department Korea Institute of Materials Science (KIMS) Changwon Gyeongnam 51508 South Korea

References

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