DataVXSmallPaper
journal article·2018-08Open access

Cancer Therapy: Synergized Multimodal Therapy for Safe and Effective Reversal of Cancer Multidrug Resistance Based on Low‐Level Photothermal and Photodynamic Effects (Small 31/2018)

Luming Xu, Jia Liu, Jiangbo Xi, Qilin Li, Bingcheng Chang, Xianming Duan, Guobin Wang, Shuai Wang, Zheng Wang, Lin Wang

Small· Volume 14· Issue 31
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Source abstract

Abstract

In article number 1800785, Guobin Wang, Shuai Wang, Zheng Wang, Lin Wang, and co-workers fabricate a versatile nanoplatform composed of gold-nanodot-decorated hollow carbon nanospheres with hyaluronic acid coating (AuHCNs-HA). Such a nanoplatform serves as a trimodal drug delivery and therapeutic system. Using this system, their work reveals that weak photothermal effects and weak photodynamic effects are quantitatively and functionally sufficient to augment chemotherapy efficacy towards effectively reversing cancer multi-drug resistance with excellent biosafety.
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Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Supramolecular Self-Assembly in Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Research Center for Tissue Engineering and Regenerative Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

Key laboratory of Material Chemistry for Energy Conversion and Storage of Ministry of Education Department of Chemistry and Chemical Engineering Huazhong University of Science and Technology Wuhan 430074 China

School of Chemistry and Environmental Engineering Wuhan Institute of Technology Wuhan 430205 China

Department of Gastrointestinal Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

Minimally Invasive Surgery Medical Research Center of Hubei Province Wuhan 430022 China

Department of Clinical Laboratory Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 China

References

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