journal article·2018-02Open access

Stem Cell Imaging: Effective Labeling of Primary Somatic Stem Cells with BaTiO3 Nanocrystals for Second Harmonic Generation Imaging (Small 8/2018)

Nami Sugiyama, Ali Y. Sonay, Roxanne Tussiwand, Bruce E. Cohen, Periklis Pantazis

Small· Volume 14· Issue 8

Abstract

In article number 1703386, Periklis Pantazis and co-workers use Second Harmonic Generating (SHG) nanoprobes to label, with high contrast, clinically relevant hematopoietic stem cells (HSCs) by establishing an effective cell labeling procedure without affecting the HSC differentiation potential. Quantitative single-cell analysis reveals that freshly isolated HSCs show limited nanoparticle uptake, whereas HSCs entering a proliferative state display a 2.5-fold increase in uptake.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research · Cancer Cells and Metastasis

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Affiliations

Department of Biosystems Science and Engineering (D‐BSSE) Eidgenössische Technische Hochschule (ETH) Zurich 4058 Basel Switzerland

Department of Biomedicine University of Basel 4058 Basel Switzerland

The Molecular Foundry Lawrence Berkeley National Laboratory Berkeley CA 94720 USA

References

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