journal article·2016-10

Chemotherapy: Amino Acid Metabolism Abnormity and Microenvironment Variation Mediated Targeting and Controlled Glioma Chemotherapy (Small 40/2016)

Sai An, Xiuhong Lu, Weili Zhao, Tao Sun, Yu Zhang, Yifei Lu, Chen Jiang

Small· Volume 12· Issue 40
Publisher page

Abstract

The brain requires large amounts of amino acids, which normally get across the brain capillaries through transporters and are then used by brain cells. When glioma takes place, tumor cells sitting right outside brain capillaries are always ready to grab the food of brain cells. Based on this, on page 5633, C. Jiang and co-workers decorate therapeutic nanoparticles with amino acid derivates, making them act as stealth nanoparticles to be swallowed by tumor cells for glioma therapy.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Amino Acid Enzymes and Metabolism

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Smart Drug Delivery Ministry of Education Department of Pharmaceutics School of Pharmacy Fudan University 826 Zhangheng Road Shanghai 201203 P. R. China

Department of Medical Chemistry School of Pharmacy Fudan University 826 Zhangheng Road Shanghai 201203 P. R. China

State Key Laboratory of Medical Neurobiology Fudan University 826 Zhangheng Road Shanghai 201203 P. R. China

References

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