DataVXSmallPaper
journal article·2016-09Open access

Neural Stem Cells: Radially Aligned Electrospun Fibers with Continuous Gradient of SDF1α for the Guidance of Neural Stem Cells (Small 36/2016)

Xiaoran Li, Mengyuan Li, Jie Sun, Yan Zhuang, Jiajia Shi, Dongwei Guan, Yanyan Chen, Jianwu Dai

Small· Volume 12· Issue 36
Publisher pageOpen full text
Source abstract

Abstract

A tubular conduit composed of radially aligned electrospun fibers with gradient is transplanted into the gap of the transected spinal cord. The endogenous neural stem cells in the two ends of spinal cord sense the gradient, and migrate toward the lesion site. This class of gradient scaffolds, presented by J. Dai and co-workers on page 5009, can potentially be employed for nerve regeneration guidance.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nerve injury and regeneration · Electrospun Nanofibers in Biomedical Applications · Mesenchymal stem cell research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory for Nano‐Bio Interface Research Division of Nanobiomedicine Suzhou Institute of Nano‐Tech and Nano‐Bionics Chinese Academy of Sciences Suzhou 215123 China

School of Life Sciences Shanghai University Shanghai 200444 China

Institute of Combined Injury State Key Laboratory of Trauma Burns and Combined Injury College of Preventive Medicine Third Military Medical University Chongqing 400038 China

Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100080 China

References

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